教員情報 - 佐藤　哲也 | 埼玉医科大学

教員情報トップぺージ

研究課題・受託研究・科研費

現在の専門分野

著書

（最終更新日：2025-08-21 15:46:50）

  サトウ　テツヤ   SATO Tetsuya
  佐藤　哲也
   所属   埼玉医科大学医学部中央研究施設

職種准教授

■ 研究課題・受託研究・科研費

1.	2014～2015	環境 DNA から多種多様な生物種を同定する新規手法への挑戦挑戦的萌芽研究
2.	2016～2017	染色体高次構造情報を用いた疾患原因遺伝子予測システムの構築
3.	2016～2017	臨床ビッグデータを利用したがん治療用抗体医薬の新規ターゲットの発見
4.	2018～2020	RNAスプライシングパターンに基づく抗体医薬の新規標的分子探索法の開発基盤研究（C）（一般）
5.	2018～2020	一塩基多型特異的RNAスプライシングの探索と応用基盤研究（C）（特設分野研究）

■ 現在の専門分野

システムゲノム科学, 生命、健康、医療情報学　（キーワード：バイオインフォマティクス、ゲノム解析、エピゲノム解析、シングルセル解析、HLA解析）

■ 著書

1.	単行本	Chromatin Immunoprecipitation Sequencing (ChIP-seq) for Detecting Histone Modifications and Modifiers, Methods Mol Biol 2022/09/30
2.	単行本	Improvement of the mirrortree method by extracting evolutionary information, Sequence and Genome Analysis: Method and Applications 2011/03/18
3.	単行本	大腸癌の個性を際立たせる発現遺伝子の変化〜全発現遺伝子を研究対象としてみえてきたこと〜「大腸癌FRONTIER」 2010/09/01
4.	単行本	計算による相互作用の予測「分子間相互作用解析ハンドブック」 2007/09/28

■ 学術雑誌

1.	学術雑誌(原著)	Sall1 regulates microtubule acetylation in mesenchymal cells during mouse urethral development 2025/04/28
2.	学術雑誌(原著)	Male-Dominant Spinal Microglia Contribute to Neuropathic Pain by Producing CC-Chemokine Ligand 4 Following Peripheral Nerve Injury 2025/03/23
3.	学術雑誌(原著)	Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells 2024/11/06
4.	学術雑誌(原著)	Drosophila transcription factor NF-Y suppresses transcription of the lipase 4 gene, a key gene for lipid storage 2022/11
5.	学術雑誌(原著)	Sexual fate of murine external genitalia development: conserved transcriptional competency for male-biased genes in both sexes 2021/06
6.	学術雑誌(原著)	LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα 2021/05
7.	学術雑誌(原著)	Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants 2019/06
8.	学術雑誌(原著)	Zfp281 shapes the transcriptome of trophoblast stem cells and is essential for placental development 2019/05
9.	学術雑誌(原著)	miR-124 dosage regulates prefrontal cortex function by dopaminergic modulation 2019/03
10.	学術雑誌(原著)	Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones 2019/03
11.	学術雑誌(原著)	Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells 2018/12
12.	学術雑誌(原著)	Pan-cancer analysis of intratumor heterogeneity associated with patient prognosis using multidimensional measures 2018/12
13.	学術雑誌(原著)	Prognostic Impact of Immune-Related Gene Expression in Preoperative Peripheral Blood from Gastric Cancer Patients 2018/11
14.	学術雑誌(原著)	Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer 2018/09
15.	学術雑誌(原著)	The Autism-Related Protein CHD8 Cooperates with C/EBPβ to Regulate Adipogenesis 2018/05
16.	学術雑誌(原著)	Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids 2018/03
17.	学術雑誌(原著)	Identification of miR-305, a microRNA that promotes aging, and its target mRNAs in Drosophila 2018/02
18.	学術雑誌(原著)	Derivation of Human Trophoblast Stem Cells 2018/01
19.	学術雑誌(原著)	Histone methyltransferase G9a is a key regulator of the starvation-induced behaviors in Drosophila melanogaster 2017/11
20.	学術雑誌(原著)	Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells 2017/11
21.	学術雑誌(原著)	Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14 2017/11
22.	学術雑誌(原著)	The novel heme-dependent inducible protein, SRRD regulates heme biosynthesis and circadian rhythms 2017/10
23.	学術雑誌(原著)	Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development 2017/05
24.	学術雑誌(原著)	A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo 2017/03
25.	学術雑誌(原著)	Control of tissue size and development by a regulatory element in the yorkie 3'UTR 2017/03
26.	学術雑誌(原著)	Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells 2017/03
27.	学術雑誌(原著)	Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells 2017/02
28.	学術雑誌(原著)	Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta 2016/11
29.	学術雑誌(原著)	Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains 2016/11
30.	学術雑誌(原著)	CHD8 haploinsufficiency results in autistic-like phenotypes in miceNature 2016/09
31.	学術雑誌(原著)	MRG15 is required for pre-mRNA splicing and spermatogenesis 2016/09
32.	学術雑誌(原著)	Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat 2016/08
33.	学術雑誌(原著)	TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin 2016/05
34.	学術雑誌(原著)	Isolation and characterization of fetal Leydig progenitor cells of male mice 2016/03
35.	学術雑誌(原著)	Androgen regulates Mafb expression through its 3'UTR during mouse urethral masculinization. 2016/02
36.	学術雑誌(原著)	ChromContact: A web tool for analyzing spatial contact of chromosomes from Hi-C data 2015/12
37.	学術雑誌(原著)	Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis 2015/11
38.	学術雑誌(原著)	Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus 2015/11
39.	学術雑誌(原著)	DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis 2015/08
40.	学術雑誌(原著)	foxl3 is a germ cell-intrinsic factor involved in sperm-egg fate decision in medaka 2015/07
41.	学術雑誌(原著)	GenomeCons: a web server for manipulating multiple genome sequence alignments and their consensus sequences 2015/04
42.	学術雑誌(原著)	A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice 2015/01
43.	学術雑誌(原著)	Genome-wide analysis of histone modifications in human endometrial stromal cells 2014/10
44.	学術雑誌(原著)	Identification of Myelin Transcription Factor 1 (MyT1) as a Subunit of the Neural Cell Type-specific Lysine-specific Demethylase 1 (LSD1) Complex 2014/06
45.	学術雑誌(原著)	Characterization of common marmoset dysgerminoma-like tumor induced by the lentiviral expression of reprogramming factors 2014/04
46.	学術雑誌(原著)	Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1 2014/04
47.	学術雑誌(原著)	Microarray analysis reveals that high mobility group A1 is involved in colorectal cancer metastasis 2013/09
48.	学術雑誌(原著)	Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis 2013/04
49.	学術雑誌(原著)	The rs6983267 SNP Is Associated with MYC Transcription Efficiency, Which Promotes Progression and Worsens Prognosis of Colorectal Cancer 2013/04
50.	学術雑誌(原著)	Increased Risk for CRC in Diabetic Patients with the Nonrisk Allele of SNPs at 8q24 2012/09
51.	学術雑誌(原著)	Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma 2012/07
52.	学術雑誌(原著)	Microarray analysis of colorectal cancer stromal tissue reveals upregulation of two oncogenic miRNA clusters 2012/06
53.	学術雑誌(原著)	Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells 2011/07
54.	学術雑誌(原著)	Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis 2010/12
55.	学術雑誌(原著)	FANCD2 mRNA Overexpression is a Bona Fide Indicator of Lymph Node Metastasis in Human Colorectal Cancer 2010/09
56.	学術雑誌(原著)	Long-term culture following ES-like gene-induced reprogramming elicits an aggressive phenotype in mutated cholangiocellular carcinoma cells 2010/04
57.	学術雑誌(原著)	Loss of FBXW7, a Cell Cycle Regulating Gene, in Colorectal Cancer: Clinical Significance 2010/04
58.	学術雑誌(原著)	Over-expression of SUGT1 in human colorectal cancer and its clinicopathological significance 2010/03
59.	学術雑誌(原著)	Gtr1p differentially associates with Gtr2p and Ego1p 2009/05
60.	学術雑誌(原著)	Prediction of missing enzyme genes in bacterial metabolic network: a reconstruction of lysine degradation pathway of Pseudomonas aeruginosa 2007/05
61.	学術雑誌(原著)	ストレス蛋白質遺伝子のプロモーター活性の可視化と評価 2007/04
62.	学術雑誌(総説)	タンパク質間相互作用の共進化情報に基づく予測 2007/01
63.	学術雑誌(原著)	Partial correlation coefficient between distance matrices as a new indicator of protein–protein interactions 2006/10
64.	学術雑誌(原著)	The inference of protein–protein interactions by evolutionary analysis is improved by excluding the information about the phylogenetic relationships 2005/09
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■ 学会発表

1.	脾臓NR5A1陽性細胞の経時的単一細胞解析（ポスター，一般） 2025/03/17
2.	Cell Cycle Arrest and CCN2 Expression in Proximal Tubular Epithelial Cells in a Mouse CKD Model （ポスター，一般） 2024/10/24
3.	抗酸化蛋白、Peroxiredoxin1は腎線維化の新規トリガーである（口頭発表，一般） 2024/06/30
4.	公共シングルセルRNA－Seqデータを活用した腎線維化トリガー因子の探索（ポスター，一般） 2024/06/28
5.	脾臓の脾洞および辺縁洞内皮細胞におけるAD4BP/SF-1/NR5A1の役割（口頭発表，一般） 2022/12/02
6.	Full-resolution HLA Class I Allele and Haplotype Frequencies in 2,200 Healthy Japanese （口頭発表，シンポジウム・ワークショップ・パネルディスカッション等） 2022/09/18
7.	MS/MS Clusteringを用いた生体試料中抗体における多様性評価法の開発（ポスター，一般） 2022/06/22
8.	HLA-E, HLA-FおよびHLA-Gのアレル網羅的な遺伝子全長解析方法の開発（ポスター，一般） 2020/11/18
9.	ロングリードシーケンサーを利用した高解像度KIRアレルタイピグ解析（ポスター，一般） 2019/11/06
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■ 専門医・専門性キーワード

専門医取得の有無：無し
バイオインフォマティクス
ゲノム解析
エピゲノム解析
シングルセル解析
HLA解析