イノウエ イクオ   INOUE Ikuo
  井上 郁夫
   所属   埼玉医科大学  医学部 教職員・学生健康推進センター
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling.
掲載誌名 正式名:Free radical biology&medicine
略  称:Free Radic Biol Med
ISSNコード:1873459608915849
掲載区分国外
巻・号・頁 156,45-56頁
著者・共著者 Teratani Toshiaki, Tomita Kengo, Toma-Fukai Sachiko, Nakamura Yutaro, Itoh Toshimasa, Shimizu Hikaru, Shiraishi Yasunaga, Sugihara Nao, Higashiyama Masaaki, Shimizu Takahiko, Inoue Ikuo, Takenaka Yasuhiro, Hokari Ryota, Adachi Takeshi, Shimizu Toshiyuki, Miura Soichiro, Kanai Takanori
発行年月 2020/06
概要 The nuclear receptor peroxisome proliferator-activated receptor (PPAR)γ has been implicated in the pathogenesis of various human diseases including fatty liver. Although nuclear translocation of PPARγ plays an important role in PPARγ signaling, details of the translocation mechanisms have not been elucidated. Here we demonstrate that PPARγ2 translocates to the nucleus and activates signal transduction through H2
DOI 10.1016/j.freeradbiomed.2020.06.005
PMID 32553752