スズキ オキヒデ
SUZUKI Okihide
鈴木 興秀 所属 埼玉医科大学 医学部 総合医療センター ゲノム診療科 職種 専任講師 |
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論文種別 | 学術雑誌(症例報告) |
言語種別 | 日本語 |
査読の有無 | 査読あり |
表題 | [Evaluation of BRAF V600E Mutations in High-Level Microsatellite Instability(MSI-H)Colon Cancer - Comparison Between Genetic Testing and Immunohistochemical Staining]. |
掲載誌名 | 正式名:Gan to kagaku ryoho. Cancer&chemotherapy 略 称:Gan To Kagaku Ryoho ISSNコード:0385068403850684 |
掲載区分 | 国内 |
巻・号・頁 | 43(12),1693-1695頁 |
著者・共著者 | Sakimoto Takehiko, Chika Noriyasu, Suzuki Okihide, Ishibashi Keiichiro, Tachikawa Tetsuhiko, Akagi Kiwamu, Eguchi Hidetaka, Okazaki Yasushi, Ishida Hideyuki |
発行年月 | 2016/11 |
概要 | BRAF V600E mutation plays an important role in the serrated neoplasia pathway of colorectal tumorigenesis and is a negative predictive factor for chemotherapy response as well as a prognostic factor in patients with colorectal cancer. To evaluate BRAF V600E mutations, a conventional polymerase chain reaction(PCR)is performed but recently immunohistochemistry (IHC)with a BRAF antibody |
PMID | 28133101 |