カイダ ケンイチ   KAIDA Kenichi
  海田 賢一
   所属   埼玉医科大学  医学部 総合医療センター 脳神経内科
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 Guillain-Barré syndrome associated with IgG monospecific to ganglioside GD1b
掲載誌名 正式名:Neurology
ISSNコード:00283878
出版社 Lippincott Williams and Wilkins
巻・号・頁 56(9),1227-1229頁
著者・共著者 T. Miyazaki,Susumu Kusunoki,K. Kaida,M. Shiina,I. Kanazawa
発行年月 2001/05
概要 The authors examined serum antiglycolipid antibodies in 445 patients with Guillain-Barré syndrome (GBS). Among them, nine had anti-GD1b IgG antibodies with no reactivity to other glycolipids tested. All those patients had sensory disturbance, and none had the primary axonal form. Anti-GD1b IgG antibodies may bind to primary sensory neurons and paranodal myelin, where GD1b is localized, and be involved in the pathogenesis of sensory disturbance and demyelination. However, more study is needed to substantiate the roles of anti-GD1b IgG antibodies.
DOI 10.1212/WNL.56.9.1227
PMID 11342695