カイダ ケンイチ   KAIDA Kenichi
  海田 賢一
   所属   埼玉医科大学  医学部 総合医療センター 脳神経内科
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 An atypical case of anti-nmda receptor encephalitis: Predominant parkinsonism and persisting micrographia without oro-facial dyskinesia
掲載誌名 正式名:Internal Medicine
ISSNコード:13497235
出版社 Japanese Society of Internal Medicine
巻・号・頁 54(15),1927-1932頁
著者・共著者 Masato Kadoya,Akiko Kadoya,Hiroyuki Onoue,Katsunori Ikewaki,Kenichi Kaida
発行年月 2015/08
概要 We describe the case of a 46-year-old man with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis with prominent parkinsonism. The patient presented with psychiatric symptoms followed by epileptic seizure and parkinsonism including micrographia. Magnetic resonance imaging (MRI) revealed lesions in the bilateral medial temporal lobes and basal ganglia on fluid-attenuated inversion recovery images. His symptoms and MRI findings were ameliorated by immunotherapy but then relapsed. After retreatment, his parkinsonism gradually improved except for the micrographia. This is an atypical case of anti-NMDAR encephalitis in that the patient showed prominent and refractory parkinsonism, thus indicating that the clinical diversity of anti-NMDAR encephalitis is greater than expected.
DOI 10.2169/internalmedicine.54.3757
PMID 26234239