イワセ　サトル   Iwase Satoru   岩瀬　哲    所属   埼玉医科大学  医学部 緩和医療科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Reversibility of delirium in Ill-hospitalized cancer patients: Does underlying etiology matter?
掲載誌名	正式名：Cancer Medicine 略　 称：Cancer Med. ISSNコード：20457634
掲載区分	国外
出版社	John Wiley & Sons Ltd
巻・号・頁	9(1),19-26頁
著者・共著者	Matsuda Y, Maeda I, Morita T, Yamauchi T, Sakashita A, Watanabe H, Kaneishi K, Amano K, Iwase S, Ogawa A, Yoshiuchi K
発行年月	2020/01/01
概要	We conducted a secondary analysis of a multicenter, prospective, observational study to estimate the effectiveness of pharmacotherapy for delirium. Participants were cancer patients with delirium. We assessed the Delirium Rating Scale, Revised-98 (DRS-R98) severity scale score at baseline and three days after pharmacotherapy initiation. Delirium resolution was defined as a DRS-R98 severity scale score ≤9, and improvement was defined as ≥50% reduction at Day 3. Delirium caused by nonrespiratory infection may be reversible, while delirium associated with dehydration, organic damage to the CNS, hypoxia, or hyponatremia seems to be irreversible in ill-hospitalized cancer patients.