コレマツ セイゴ   KOREMATSU Seigo
  是松 聖悟
   所属   埼玉医科大学  医学部 総合医療センター 小児科(小児科、総合周産期母子医療センター新生児科、小児救命救急センター)
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 Risks of antipyretics in young children with fever due to infectious disease
掲載誌名 正式名:Pediatrics International
ISSNコード:1442200X
巻・号・頁 36(4),375-378頁
著者・共著者 TETSU SUGIMURA,TAMOTSU FUJIMOTO,HIROKI MOTOYAMA,TAKANORI MARUOKA,SEIGOU KOREMATU,YUKI ASAKUNO,HIROSHI HAYAKAWA
発行年月 1994
概要 The objective of this study was to determine whether paracetamol (acetaminophen) affects the outcome of children with fever due to bacterial infectious disease. A total of 208 outpatients aged 6 months to 15 years with pyrexia due to bacterial infection who had been examined at the Fujimoto Children's Hospital from March 1992 to May 1992. The number of antipyretic doses of paracetamol (10 mg/kg) a day received within 3 days of illness in the patients with acute fever (≥ = 38°C) was investigated. In this study, the patients were divided into two groups: (i) the pneumonia group, which consisted of 101 patients who were subsequently diagnosed as having pneumonia during their illness and (ii) the control group, which consisted of 107 patients who were subsequently diagnosed as having illness with fever that did not progress to pneumonia. The mean number of daily doses was significantly higher for the pneumonia group (2.52 ± 0.80) than for the control group (1.37 ± 0.72, P&lt 0.001). There was no significant difference between the pneumonia group and the control group in body temperature during acute fever (38.7 ± 0.65 vs 38.8 ± 0.54°C). The data suggest that frequent administ
DOI 10.1111/j.1442-200X.1994.tb03204.x
PMID 7941999