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コレマツ セイゴ
KOREMATSU Seigo
是松 聖悟 所属 埼玉医科大学 医学部 総合医療センター 小児科（小児科､総合周産期母子医療センター新生児科、小児救命救急センター） 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Month of birth and prevalence of atopic dermatitis in schoolchildren: Dry skin in early infancy as a possible etiologic factor |
| 掲載誌名 | 正式名：Journal of Allergy and Clinical Immunology ISSNコード：00916749 |
| 出版社 | Mosby Inc. |
| 巻・号・頁 | 103(6),1148-1152頁 |
| 著者・共著者 | Takashi Kusunoki,Kouichi Asai,Masashi Harazaki,Seigo Korematsu,Susumu Hosoi |
| 発行年月 | 1999 |
| 概要 | Background: Month of birth has been shown to affect later development of allergic diseases. Objective: We sought to evaluate the relationship between month of birth and the prevalence of atopic dermatitis (AD) in a large-scale general population of schoolchildren and to elucidate the possible mechanism for this relationship. Methods: Questionnaire data on the prevalence of allergic diseases were obtained for 33,725 schoolchildren aged 7 to 15 years. In a separate study the water-holding capacity of 'uninvolved' skin was compared for children with and without AD. Results: We found striking differences in the prevalence of AD according to the month of birth (X2 = 34.9, P< .0001). Overall, those born in autumn showed the highest (7.5%), and those born in spring showed the lowest (5.5%), prevalence of AD. There was little or no such tendency for the prevalence of bronchial asthma (X2 = 17.2, P = .103) and allergic rhinitis (X2 = 24, P = .01). We found no statistical variation across birth month in the ratio of AD with no other allergic disease/total AD, indicating that this deviation was observed whatever the allergic predisposition of the subjects. In a separate study a significan |
| DOI | 10.1016/S0091-6749(99)70191-0 |
| PMID | 10359898 |