コレマツ　セイゴ   KOREMATSU Seigo   是松　聖悟    所属   埼玉医科大学  医学部 総合医療センター　小児科（小児科､総合周産期母子医療センター新生児科、小児救命救急センター）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Detection of platelet-binding anti-measles and anti-rubella virus IgG antibodies in infants with vaccine-induced thrombocytopenic purpura.
掲載誌名	正式名：Vaccine ISSNコード：0264410X
出版社	ELSEVIER SCI LTD
巻・号・頁	29(31),4878-80頁
著者・共著者	Naho Okazaki,Masahiro Takeguchi,Kohji Sonoda,Yohsuke Handa,Tatsuo Kakiuchi,Hiroaki Miyahara,Kensuke Akiyoshi,Seigo Korematsu,Soichi Suenobu,Tatsuro Izumi
発行年月	2011/07
概要	A 15-month-old infant presented with thrombocytopenic purpura after sequential administration of measles-rubella combined vaccine, varicella vaccine and mumps vaccine every 4 weeks. Her thrombocytopenia persisted for more than 12 months. Both anti-measles and anti-rubella virus IgG antibodies were detected in the patient's-isolated platelets on day 154 of illness, which were not detected when there was a reduction of the serum IgG antibody titers on days 298 and 373 of illness, respectively.We also detected the isolated platelet-binding anti-measles and anti-rubella virus IgG antibodies in two other pediatric patients. This is the first report demonstrating direct evidence of vaccine-induced thrombocytopenic purpura.
DOI	10.1016/j.vaccine.2011.04.036
PMID	21539881