コレマツ　セイゴ   KOREMATSU Seigo   是松　聖悟    所属   埼玉医科大学  医学部 総合医療センター　小児科（小児科､総合周産期母子医療センター新生児科、小児救命救急センター）    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Age-specific sex-related differences in infections: a statistical analysis of national surveillance data in Japan.
掲載誌名	正式名：PloS one ISSNコード：19326203
出版社	PUBLIC LIBRARY SCIENCE
巻・号・頁	7(7),e42261頁
著者・共著者	Nobuoki Eshima,Osamu Tokumaru,Shohei Hara,Kira Bacal,Seigo Korematsu,Shigeru Karukaya,Kiyo Uruma,Nobuhiko Okabe,Toyojiro Matsuishi
発行年月	2012
概要	BACKGROUND: To prevent and control infectious diseases, it is important to understand how sex and age influence morbidity rates, but consistent clear descriptions of differences in the reported incidence of infectious diseases in terms of sex and age are sparse. METHODS AND FINDINGS: Data from the Japanese surveillance system for infectious diseases from 2000 to 2009 were used in the analysis of seven viral and four bacterial infectious diseases with relatively large impact on the Japanese community. The male-to-female morbidity (MFM) ratios in different age groups were estimated to compare incidence rates of symptomatic reported infection between the sexes at different ages. MFM ratios were>1 for five viral infections out of seven in childhood, i.e. male children were more frequently reported as infected than females with pharyngoconjunctival fever, herpangina, hand-foot-and-mouth disease, mumps, and varicella. More males were also reported to be infected with erythema infectiosum and exanthema subitum, but only in children 1 year of age. By contrast, in adulthood the MFM ratios decreased to<1 for all of the viral infections above except varicella, i.e. adult women were more fre
DOI	10.1371/journal.pone.0042261
PMID	22848753