イチキ　ヨシノブ   ICHIKI Yoshinobu   市来　嘉伸    所属   埼玉医科大学  医学部 国際医療センター　呼吸器外科    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Significance of Smoking as a Postoperative Prognostic Factor in Patients with Non-small Cell Lung Cancer.
掲載誌名	正式名：Journal of thoracic oncology : official publication ofthe International Association for the Study of Lung Cancer
巻・号・頁	3(10),1127-32頁
著者・共著者	Takeshi Hanagiri,Kenji Sugio,Makiko Mizukami,Yoshinobu Ichiki,Masakazu Sugaya,Manabu Yasuda,Mitsuhiro Takenoyama,Kosei Yasumoto
発行年月	2008/10
概要	INTRODUCTION: In this study, we investigated the influence of smoking on the postoperative prognosis in patients with non-small cell lung cancer. METHODS: The subjects consisted of 770 patients who underwent a resection of lung cancer in our department between 1994 and 2005. We compared the clinico-pathological findings between the smoking and never-smoking groups. The pack-year index (PYI) was used as a smoking index. RESULTS: The smoking group consisted of 569 patients (74%), and the never-smoking group consisted of 201 patients (26%). The smokers were composed of 492 men and 77 women. Among the adenocarcinoma patients, there were 293 (61%) smokers and 185 (39%) never-smokers. The patients with squamous cell carcinoma included 204 (95%) smokers and 10 (5%) never-smokers. The proportion of patients with stage IA disease was significantly higher in the never-smokers than that of the smokers. The 5-year survival rate after surgery was 66% in the never-smoking group; however, the rates were 56% in patients with a PYI more than or equal to 20, and 55% in those with PYI more than 20. Seventy-nine (13.9%) patients in the smoking group and seven (3.5%) patients in the never-smoking group
DOI	10.1097/JTO.0b013e318186fafb
PMID	18827608