イチキ　ヨシノブ   ICHIKI Yoshinobu   市来　嘉伸    所属   埼玉医科大学  医学部 国際医療センター　呼吸器外科    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Should Lung-Sparing Surgery Be the Standard Procedure for Malignant Pleural Mesothelioma?
掲載誌名	正式名：Journal of clinical medicine
巻・号・頁	9(7)
著者・共著者	Yoshinobu Ichiki,Hidenori Goto,Takashi Fukuyama,Kozo Nakanishi
発行年月	2020/07
概要	BACKGROUND: Surgical procedures for malignant pleural mesothelioma (MPM) include extrapleural pneumonectomy (EPP), extended pleurectomy/decortication (P/D) and P/D. EPP has been applied to MPM for a long time, but the postoperative status is extremely poor due to the loss of one whole lung. We compared the mortality, morbidity and median survival time (MST) of lung-sparing surgery (extended P/D or P/D) and lung-sacrificing surgery (EPP) for MPM by performing a systematic review. METHODS: We extracted the number of events and patients from the literature identified in electronic databases. Ultimately, 15 reports were selected, and 2674 MPM patients, including 1434 patients undergoing EPP and 1240 patients undergoing extended P/D or P/D, were analyzed. RESULTS: Our systematic review showed that lung-sparing surgery was significantly superior to lung-sacrificing surgery in both the surgical-related mortality (extended P/D vs. EPP: 3.19% vs. 7.65%, p<0.01; P/D vs. EPP: 1.85% vs. 7.34%, p<0.01) and morbidity (extended P/D vs. EPP: 35.7% vs. 60.0%, p<0.01; P/D vs. EPP: 9.52% vs. 20.89%, p<0.01). Lung-sparing surgery was not inferior to EPP in terms ofMST. CONCLUSION: Although no
DOI	10.3390/jcm9072153
PMID	32650433