ジュウジョウ ケンタロウ
JUJO Kentaro
重城 健太郎 所属 埼玉医科大学 医学部 総合医療センター 心臓内科 職種 教授 |
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論文種別 | 学術雑誌(原著) |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Effect of Hemodialysis on 7-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation |
掲載誌名 | 正式名:CIRCULATION JOURNAL ISSNコード:13469843 |
出版社 | JAPANESE CIRCULATION SOC |
巻・号・頁 | 79(10),2169-+頁 |
著者・共著者 | Nozima Buronova,Kazuho Kamishima,Junichi Yamaguchi,Kentaro Jujo,Erisa Watanabe,Yusuke Inagaki,Shohei Kishi,Akira Wada,Shinya Hatakeyama,Masahiro Watanabe,Masashi Nakao,Dai Okayama,Hiroyuki Arashi,Norihiro Yamada,Atsushi Takagi,Hiroshi Ogawa,Nobuhisa Hagiwara |
発行年月 | 2015/10 |
概要 | Background: Hemodialysis (HD) patients are reported to show poor clinical outcomes after percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES) compared with non-HD patients and their long-term prognosis remains unclear.Methods and Results: We prospectively enrolled 489 consecutive patients undergoing PCI with SES and performed a retrospective analysis focusing on HD patients. Median follow-up was 7.0 years (interquartile range, 4.2-7.9) and the follow-up rate was 100%. At the 7-year follow-up, the cumulative incidences of all-cause death, target lesion revascularization (TLR) and major adverse cardiac events (MACE) were significantly higher in HD patients than in non-HD patients (HD vs. non-HD=34.7% vs. 9.6%, 42.6% vs. 10.2% and 75.3% vs. 24.4%, respectively; log-rank P<0.001). Cox-proportional hazard analysis revealed that independent predictors of all-cause death were HD (hazard ratio [HR]2.88, 95% confidence interval [CI]: 1.39-6.00), insulin-treated diabetes mellitus (HR 2.19, 95% CI: 1.17-4.11), heart failure (HR 2.58, 95% CI: 1.25-5.32) and older age (HR 1.06/1-age, 95% CI: 1.02-1.10). Moreover, HD was an independent predictor of TLR (HR 3.63, 95% C |
DOI | 10.1253/circj.CJ-15-0113 |