ジュウジョウ ケンタロウ   JUJO Kentaro
  重城 健太郎
   所属   埼玉医科大学  医学部 総合医療センター 心臓内科
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 Effect of Hemodialysis on 7-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation
掲載誌名 正式名:CIRCULATION JOURNAL
ISSNコード:13469843
出版社 JAPANESE CIRCULATION SOC
巻・号・頁 79(10),2169-+頁
著者・共著者 Nozima Buronova,Kazuho Kamishima,Junichi Yamaguchi,Kentaro Jujo,Erisa Watanabe,Yusuke Inagaki,Shohei Kishi,Akira Wada,Shinya Hatakeyama,Masahiro Watanabe,Masashi Nakao,Dai Okayama,Hiroyuki Arashi,Norihiro Yamada,Atsushi Takagi,Hiroshi Ogawa,Nobuhisa Hagiwara
発行年月 2015/10
概要 Background: Hemodialysis (HD) patients are reported to show poor clinical outcomes after percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES) compared with non-HD patients and their long-term prognosis remains unclear.Methods and Results: We prospectively enrolled 489 consecutive patients undergoing PCI with SES and performed a retrospective analysis focusing on HD patients. Median follow-up was 7.0 years (interquartile range, 4.2-7.9) and the follow-up rate was 100%. At the 7-year follow-up, the cumulative incidences of all-cause death, target lesion revascularization (TLR) and major adverse cardiac events (MACE) were significantly higher in HD patients than in non-HD patients (HD vs. non-HD=34.7% vs. 9.6%, 42.6% vs. 10.2% and 75.3% vs. 24.4%, respectively; log-rank P<0.001). Cox-proportional hazard analysis revealed that independent predictors of all-cause death were HD (hazard ratio [HR]2.88, 95% confidence interval [CI]: 1.39-6.00), insulin-treated diabetes mellitus (HR 2.19, 95% CI: 1.17-4.11), heart failure (HR 2.58, 95% CI: 1.25-5.32) and older age (HR 1.06/1-age, 95% CI: 1.02-1.10). Moreover, HD was an independent predictor of TLR (HR 3.63, 95% C
DOI 10.1253/circj.CJ-15-0113