クワバラ　ヒトシ   KUWABARA Hitoshi   桑原　斉    所属   埼玉医科大学  医学部 神経精神科・心療内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Obsessive-Compulsive Symptom Dimensions in Japanese Tourette Syndrome Subjects
掲載誌名	正式名：CNS SPECTRUMS ISSNコード：10928529
出版社	M B L COMMUNICATIONS, INC
巻・号・頁	15(5),296-303頁
著者・共著者	Yukiko Kano,Toshiaki Kono,Kurie Shishikura,Chizue Konno,Hitoshi Kuwabara,Masataka Ohta,Maria Conceicao do Rosario
発行年月	2010/05
概要	Objectives: To investigate the current and lifetime frequency and severity of obsessive-compulsive (OC) symptom dimensions in Tourette syndrome (TS) patients, and how these dimensions affect clinical characteristics.Methods: Forty TS outpatients (29 males, 11 females) were interviewed with the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), the Yale Global Tic Severity Scale (YGTSS), the Shapiro Tourette Syndrome Severity Scale, and the Global Assessment of Functioning (GAF).Results: OC symptoms were present in 80% of the total sample. The miscellaneous and the symmetry dimensions were the most frequent at the"current"and"lifetime"surveys, respectively. The aggression dimension had the smallest difference between"worst ever"and current ratings among the all OC symptom dimensions. TS patients with the aggression dimension (n=7) had significantly lower scores in the GAF scale and higher frequencies of coprolalia. There were significant correlations between the YGTSS severity scores and specific DY-BOCS dimensions.Conclusion: OC symptoms are frequent in TS subjects and there were differences in the frequency, severity, and course of the OC symptom dimensions. The
PMID	20448520