クワバラ　ヒトシ   KUWABARA Hitoshi   桑原　斉    所属   埼玉医科大学  医学部 神経精神科・心療内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Impact of obsessive-compulsive symptoms in Tourette's syndrome on neuropsychological performance
掲載誌名	正式名：PSYCHIATRY AND CLINICAL NEUROSCIENCES ISSNコード：13231316
出版社	WILEY-BLACKWELL
巻・号・頁	66(3),195-202頁
著者・共著者	Natsumi Matsuda,Toshiaki Kono,Maiko Nonaka,Kurie Shishikura,Chizue Konno,Hitoshi Kuwabara,Takafumi Shimada,Yukiko Kano
発行年月	2012/04
概要	Aim: Although inconsistencies in neuropsychological impairments in Tourette's syndrome (TS) have been discussed with respect to comorbid disorders, such as obsessive-compulsive disorder, few studies have focused on the specific dimensions of obsessive-compulsive symptoms (OCS) related to TS, such as aggression and symmetry. The aim of this study was to explore the impact of specific TS-related OCS on neuropsychological performance.Methods: A series of neuropsychological tasks examining attention and executive functioning were performed in groups of 33 TS participants and 18 healthy controls. The neuropsychological performance of TS with Aggression OCS (n = 11) were compared to TS without Aggression OCS (n = 22) and controls by using MANCOVA controlling for age. In the same way as Aggression, we compared the performance of three groups by Symmetry: TS with Symmetry OCS (n = 14), TS without Symmetry OCS (n = 19) and controls.Results: TS participants with Aggression OCS tended to make more perseverative errors than those without. Global OCS severity and tic severity did not correlate with any neuropsychological performances. No significant differences were detected between TS partic
DOI	10.1111/j.1440-1819.2012.02319.x
PMID	22369455