クワバラ　ヒトシ   KUWABARA Hitoshi   桑原　斉    所属   埼玉医科大学  医学部 神経精神科・心療内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	The impact of tics, obsessive-compulsive symptoms, and impulsivity on global functioning in Tourette syndrome
掲載誌名	正式名：PSYCHIATRY RESEARCH ISSNコード：01651781
出版社	ELSEVIER IRELAND LTD
巻・号・頁	226(1),156-161頁
著者・共著者	Yukiko Kano,Toshiaki Kono,Natsumi Matsuda,Maiko Nonaka,Hitoshi Kuwabara,Takafumi Shimada,Kurie Shishikura,Chizue Konno,Masataka Ohta
発行年月	2015/03
概要	This study investigated the relationships between tics, obsessive-compulsive symptoms (OCS), and impulsivity, and their effects on global functioning in Japanese patients with Tourette syndrome (TS), using the dimensional approach for OCS. Fifty-three TS patients were assessed using the Yale Global Tic Severity Scale, the Dimensional Yale-Brown Obsessive-Compulsive Scale, the ImpulsivityRating Scale, and the Global Assessment of Functioning Scale. Although tic severity scores were significantly and positively correlated with OCS severity scores, impulsivity severity scores were not significantly correlated with either. The global functioning score was significantly and negatively correlated with tic and OCS severity scores. Of the 6 dimensional OCS scores, only aggression scores had a significant negative correlation with global functioning scores. A stepwise multiple regression analysis showed that only OCS severity scores were significantly associated with global functioning scores. Despite a moderate correlation between tic severity and OCS severity, the impact of OCS on global functioning was greater than that of tics. Of the OCS dimensions, only aggression had a significant i
DOI	10.1016/j.psychres.2014.12.041
PMID	25618473