クワバラ　ヒトシ   KUWABARA Hitoshi   桑原　斉    所属   埼玉医科大学  医学部 神経精神科・心療内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial.
掲載誌名	正式名：Molecular psychiatry ISSNコード：13594184
巻・号・頁	25(8),1849-1858頁
著者・共著者	Hidenori Yamasue,Takashi Okada,Toshio Munesue,Miho Kuroda,Toru Fujioka,Yota Uno,Kaori Matsumoto,Hitoshi Kuwabara,Daisuke Mori,Yuko Okamoto,Yuko Yoshimura,Yuki Kawakubo,Yuko Arioka,Masaki Kojima,Teruko Yuhi,Keiho Owada,Walid Yassin,Itaru Kushima,Seico Benner,Nanayo Ogawa,Yosuke Eriguchi,Naoko Kawano,Yukari Uemura,Maeri Yamamoto,Yukiko Kano,Kiyoto Kasai,Haruhiro Higashida,Norio Ozaki,Hirotaka Kosaka
発行年月	2020/08
概要	Although small-scale studies have described the effects of oxytocin on social deficits in autism spectrum disorder (ASD), no large-scale study has been conducted. In this randomized, parallel-group, multicenter, placebo-controlled, double-blind trial in Japan, 106 ASD individuals (18-48 y.o.) were enrolled between Jan 2015 and March 2016. Participants were randomly assigned to a 6-week intranasal oxytocin (48IU/day, n = 53) or placebo (n = 53) group.
DOI	10.1038/s41380-018-0097-2
PMID	29955161