カイダ　ケンイチ   KAIDA Kenichi   海田　賢一    所属   埼玉医科大学  医学部 総合医療センター　脳神経内科    職種   教授
論文種別	学術雑誌(症例報告)
言語種別	英語
査読の有無	査読あり
表題	Vessel Wall Magnetic Resonance Imaging Showing Intravascular Large B-cell Lymphoma Infiltration: Association with Pathological Findings.
掲載誌名	正式名：Internal Medicine 略　 称：Intern Med ISSNコード：09182918
掲載区分	国外
出版社	日本内科学会
巻・号・頁	64(11),1742-1745頁
著者・共著者	Yamamoto M, Dembo T, Sawada K, Hashimoto B, Oji S, Kaida K.
発行年月	2025/06/01
概要	A 75-year-old man presented with cognitive decline, headaches, and ataxic gait. Magnetic resonance imaging (MRI) revealed acute infarcts in multiple brain regions, and vessel wall MRI (VW-MRI) demonstrated concentric arterial wall thickening and enhancement in some intracranial arteries, initially suggesting primary central nervous system vasculitis (PCNSV). Despite immunosuppressive therapy, the patient developed further infarction. A skin biopsy revealed intravascular large B-cell lymphoma (IVLBCL), and autopsy revealed tumor cells in the arterial walls corresponding to the VW-MRI findings. This case highlights the risk of a misdiagnosis of PCNSV based solely on imaging findings and underscores the need for histological confirmation.