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カイダ ケンイチ
KAIDA Kenichi
海田 賢一 所属 埼玉医科大学 医学部 総合医療センター 脳神経内科 職種 教授 |
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| 論文種別 | 学術雑誌(症例報告) |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | A Diagnostic Approach to VZV Vasculopathy Using MR Vessel Wall Imaging. |
| 掲載誌名 | 正式名：Internal Medicine 略 称：Intern Med ISSNコード：09182918 |
| 掲載区分 | 国外 |
| 出版社 | 日本内科学会 |
| 巻・号・頁 | 64(22),3298-3301頁 |
| 著者・共著者 | Yamamoto M, Dembo T, Oji S, Kaida K. |
| 発行年月 | 2025/05/22 |
| 概要 | A 43-year-old woman with systemic lupus erythematosus on immunosuppressive therapy developed right hemiparesis and motor aphasia five months after the onset of herpes zoster. Brain magnetic resonance imaging revealed an infarction in the left anterior cerebral artery and severe middle cerebral artery (MCA) stenosis. Despite antiplatelet therapy, recurrent strokes occurred, and vessel wall imaging (VWI) showed circumferential thickening of the MCA, suggesting vasculitis. Cerebrospinal fluid revealed varicella-zoster virus (VZV) deoxyribonucleic acid (DNA) and an elevated anti-VZV IgG index, consistent with VZV vasculopathy. The administration of acyclovir and corticosteroids eliminated VZV DNA. This case highlights the risk of VZV vasculopathy in immunocompromised patients and the usefulness of VWI for its diagnosis. |