ヨツモト　ジュンコ   YOTSUMOTO Junko   四元　淳子    所属   埼玉医科大学  医学部 ゲノム医療科    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Attitudes of clinical geneticists and certified genetic counselors to genome editing and its clinical applications: A nation-wide questionnaire survey in Japan.
掲載誌名	正式名：Journal of human genetics 略　 称：J Hum Genet ISSNコード：1435232X/14345161
掲載区分	国外
巻・号・頁	64(9),945-954頁
著者・共著者	Taguchi Iku, Yamada Takahiro, Akaishi Rina, Imoto Issei, Kurosawa Kenji, Nakatani Kaname, Nomura Fumio, Hamanoue Haruka, Hyodo Maki, Murakami Hiromi, Yoshihashi Hiroshi, Yotsumoto Junko, Kosugi Shinji
発行年月	2019/09
概要	BACKGROUND: Genome editing of human embryos using CRISPR/Cas9 could prevent the transmission of hereditary diseases, but the attitudes of genetic professionals remain insufficiently examined. This study surveyed Japanese clinical geneticists and certified genetic counselors regarding this technology. RESULTS: Differences emerged regarding the technology's recognition, difficulty, and cost. Both groups worried about misuse due to insufficient information and regulations, identifying ethics, safety, and purpose as key regulatory elements. While most disapproved of physical enhancement, they supported treating severe diseases. Currently, professionals maintain a prudent attitude, mentioning genome editing only as a future possibility. CONCLUSIONS: Academic policies, legislation, and public consensus are required for embryo application. Professionals must stay updated to refine rules, education, and clinical protocols, while creating opportunities to address ethical issues.
DOI	10.1038/s10038-019-0635-z
PMID	31273322