カンダ　ショウイチロウ   KANDA Shoichiro   神田　祥一郎    所属   埼玉医科大学  医学部 小児科（小児科、新生児科）    職種   教授
論文種別	学術雑誌(総説)
言語種別	英語
査読の有無	査読あり
表題	Tyrosine kinase signaling in kidney glomerular podocytes.
掲載誌名	正式名：Journal of signal transduction 略　 称：J Signal Transduct ISSNコード：20901747/20901747
掲載区分	国外
巻・号・頁	2011,317852頁
著者・共著者	Hattori Seisuke, Kanda Shoichiro, Harita Yutaka
発行年月	2011
概要	During the last decade, several key molecules have been identified as essential components for the filtration barrier function of kidney glomerular podocytes. Mutations in genes encoding these molecules severely impair the podocyte architecture in the affected patients, leading to the development of proteinuria. Extensive investigations have been performed on the function of these molecules, which highlights the importance of tyrosine kinase signaling in the podocytes. An Src family tyrosine kinase, Fyn, plays a major role in this signaling pathway. Here, we review the current understanding of this important signal transduction system and its role in the development and the maintenance of podocytes.
DOI	10.1155/2011/317852
PMID	21776384