ハセガワ　ヒロタカ   HASEGAWA Hirotaka   長谷川　洋敬    所属   埼玉医科大学  医学部 総合医療センター　脳神経外科    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Risk analysis for delayed cerebrospinal fluid leak as a late complication of endoscopic transnasal surgery: effects of irradiation and insights into reconstruction methods.
掲載誌名	正式名：Neurosurgical review 略　 称：Neurosurg Rev ISSNコード：14372320/03445607
掲載区分	国外
巻・号・頁	48(1),463頁
著者・共著者	Umekawa Motoyuki, Hasegawa Hirotaka, Shin Masahiro, Shinya Yuki, Ono Hideaki, Kondo Kenji, Nishijima Hironobu, Saito Nobuhito
発行年月	2025/05
概要	Aggressive skull base tumors such as chordomas and high-grade meningiomas often exhibit resistance to treatment, highlighting the need for improved management combining endoscopic transnasal surgery (ETS) with adjunctive radiation therapy (RT). However, repeated ETS and RT may lead to delayed cerebrospinal fluid (CSF) leaks, posing clinical challenges. Mucosal flap-based reconstruction effectively prevented recurrence, indicating its potential advantage for managing delayed CSF leaks following ETS combined with RT.
DOI	10.1007/s10143-025-03591-1
PMID	40445436