カワムラ　ヒデマサ   KAWAMURA Hidemasa   河村　英将    所属   埼玉医科大学  医学部 総合医療センター　放射線科(画像診断・核医学科、放射線腫瘍科)    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Inoperable Pancoast tumors treated with hyperthermia-inclusive multimodality therapies
掲載誌名	正式名：LUNG CANCER ISSNコード：0169-5002
出版社	ELSEVIER IRELAND LTD
巻・号・頁	63(2),247-250頁
著者・共著者	Takeshi Ebara,Hideyuki Sakurai,Masaru Wakatsuki,Tetuso Nonaka,Hitoshi Ishikawa,Hidemasa Kawamura,Daisaku Yoshida,Mariko Shioya,Yuko Nakayama,Takashi Nakano
発行年月	2009/02
概要	Purpose: This study aimed to assess the feasibility, efficacy and complication of hyperthermia-inclusive multimodality therapies for patient with inoperable Pancoast tumor. Material and methods: Five patients with inoperable Pancoast tumor were treated with hyperthermia-inclusive multimodality therapies. They received thermoradiotherapy with/without chemotherapy. Radiation therapy was delivered using 10 MV X-rays with total dose of 68-70 Gy. In the latter half of the radiation therapy hyperthermia was performed for 2-4 sessions once a week with 8 MHz radiofrequency device. Results: For primary response, 4 tumors showed partial response to the treatment with the exception of 1 tumor who showed stable disease. Only one patient was with a short follow-up period (9 months), all other patients survived 3 years or more without recurrence. Of them, 2 patients were recognized with local recurrence at 38.7 and 42.7 months after treatment and died at 66.9 and 78.5 months after treatment. The other 2 patients are disease-free survivor for 4 and 5 years after treatment. No severe non-hematological toxicity was observed in each patient. Conclusion: These data suggested that hyperthermia-inclusive multimodality therapies might be a promising approach for inoperable Pancoast tumor. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
DOI	10.1016/j.lungcan.2008.05.023
PMID	18620779