カワムラ　ヒデマサ   KAWAMURA Hidemasa   河村　英将    所属   埼玉医科大学  医学部 総合医療センター　放射線科(画像診断・核医学科、放射線腫瘍科)    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Carbon-ion Radiotherapy for Prostate Cancer: Analysis of Morbidities and Change in Health-related Quality of Life
掲載誌名	正式名：ANTICANCER RESEARCH ISSNコード：0250-7005/1791-7530
出版社	INT INST ANTICANCER RESEARCH
巻・号・頁	35(10),5559-5566頁
著者・共著者	Hitoshi Ishikawa,Hiroyuki Katoh,Takuya Kaminuma,Hidemasa Kawamura,Kazuto Ito,Hiroshi Matsui,Junko Hirato,Nobuaki Shimizu,Yutaka Takezawa,Hiroshi Tsuji,Kazuhiro Suzuki,Tatsuya Ohno,Takashi Nakano
発行年月	2015/10
概要	Aim: To prospectively evaluate the feasibility of carbon-ion radiotherapy (C-ion RT) for prostate cancer using a new compact-sized accelerator. Patients and Methods: Seventy-six patients underwent C-ion RT at our center using a recommended dose fractionation of 57.6 GyE in 16 fractions established at the National Institute of Radiological Sciences. Health-related Quality of Life (HRQOL) assessment was also performed using the Medical Outcome Study 8-items Short Form Health Survey (SF-8) questionnaire. Results: The median follow-up time was 51 months (range=8-58 months). Grade 2 gastrointestinal and genitourinary complications developed in 1 (1.3%) and 5 (6.6%) patients, respectively. Recurrences occurred in 4 patients, and the 4-year biochemical relapse-free rate was 94.6%. The HRQOL scores after C-ion RT were objectively well-maintained. Conclusion: Irrespective of the small number of patients of the study, C-ion RT for prostate cancer using the first commercial-based accelerator reproduced the toxicity outcomes at the NIRS.
PMID	26408726