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カワムラ ヒデマサ
KAWAMURA Hidemasa
河村 英将 所属 埼玉医科大学 医学部 総合医療センター 放射線科(画像診断・核医学科、放射線腫瘍科) 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Changes in Rectal Dose Due to Alterations in Beam Angles for Setup Uncertainty and Range Uncertainty in Carbon-Ion Radiotherapy for Prostate Cancer |
| 掲載誌名 | 正式名：PLOS ONE ISSNコード：1932-6203 |
| 出版社 | PUBLIC LIBRARY SCIENCE |
| 巻・号・頁 | 11(4),e0153894頁 |
| 著者・共著者 | Yoshiki Kubota,Hidemasa Kawamura,Makoto Sakai,Ryou Tsumuraya,Mutsumi Tashiro,Ken Yusa,Nobuteru Kubo,Hiro Sato,Masahiro Kawahara,Hiroyuki Katoh,Tatsuaki Kanai,Tatsuya Ohno,Takashi Nakano |
| 発行年月 | 2016/04 |
| 概要 | Background and Purpose Carbon-ion radiotherapy of prostate cancer is challenging in patients with metal implants in one or both hips. Problems can be circumvented by using fields at oblique angles. To evaluate the influence of setup and range uncertainties accompanying oblique field angles, we calculated rectal dose changes with oblique orthogonal field angles, using a device with fixed fields at 0 degrees and 90 degrees and a rotating patient couch. Material and Methods Dose distributions were calculated at the standard angles of 0 degrees and 90 degrees, and then at 30 degrees and 60 degrees. Setup uncertainty was simulated with changes from -2 mm to +2 mm for fields in the anterior-posterior, left-right, and cranial-caudal directions, and dose changes from range uncertainty were calculated with a 1 mm water-equivalent path length added to the target isocenter in each angle. The dose distributions regarding the passive irradiation method were calculated using the K2 dose algorithm. Results The rectal volumes with 0 degrees, 30 degrees, 60 degrees, and 90 degrees field angles at 95% of the prescription dose were 3.4 +/- 0.9 cm(3), 2.8 +/- 1.1 cm(3), 2.2 +/- 0.8 cm(3), and 3.8 +/- 1.1 cm(3), respectively. As compared with 90 degrees fields, 30 degrees and 60 degrees fields had significant advantages regarding setup uncertainty and significant disadvantages regarding range uncertainty, but were not significantly different from the 90 degrees field setup and range uncertainties. Conclusions The setup and range uncertainties calculated at 30 degrees and 60 degrees field angles were not associated with a significant change in rectal dose relative to those at 90 degrees. |
| DOI | 10.1371/journal.pone.0153894 |
| PMID | 27097041 |