カワムラ ヒデマサ   KAWAMURA Hidemasa
  河村 英将
   所属   埼玉医科大学  医学部 総合医療センター 放射線科(画像診断・核医学科、放射線腫瘍科)
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読なし
表題 Radiotherapy for ductal carcinoma of the prostate: an analysis based on the Japanese radiation oncology study group survey
掲載誌名 正式名:Japanese Journal of Clinical Oncology
ISSNコード:1465-3621
掲載区分国外
出版社 Oxford University Press (OUP)
巻・号・頁 53(2),146-152頁
著者・共著者 Hidemasa Kawamura,Katsumasa Nakamura,Yasuo Yoshioka,Satoshi Itasaka,Natsuo Tomita,Masahiro Onishi,Hiromitsu Iwata,Takuya Aizawa,Koyo Kikuchi,Kenji Nagata,Kiyonao Nakamura,Kentaro Nishioka,Hiromichi Ishiyama,Shuichi Ueno,Masaki Kokubo,Hideya Yamazaki,Kenta Watanabe,Tatsuya Toyoda,Tetsuo Akimoto
発行年月 2022/12/06
概要 Abstract

Background

The clinical characteristics of prostate ductal carcinoma is still unclear, and treatment strategy has not yet been established due to its rarity. Therefore, we conducted a multicenter survey of radiation therapy for prostate ductal carcinoma in Japan.

Method

Data of patients with ductal carcinoma of the prostate treated with radiation therapy between 1996 and 2018 were extracted from the database of each facility.

Results

Fifty-two treatment records of 41 patients were collected from nine institutions. The treatment purpose and situations were varied curative intent to palliation. Twenty-eight patients received curative treatments. The median follow-up period of these patients was 68 months. Androgen deprivation therapy was combined with radiation therapy in 26 cases (93%). X-ray and particle irradiation was used. Radiation dose range was 63–78 Gy; 5-year overall survival, progression-free survival and biochemical relapse-free survival were 87.0, 79.3 and 79.3%, respectively. One patient experienced Grade 3 radiation proctitis and one experienced Grade 3 radiation cystitis. There were no Grade 4 or worse adverse events.

Conclusion

Most patient received similar treatment with adenocarcinoma of prostate, and the clinical results were compatible. For more reliable evidence, further studies are required.
DOI 10.1093/jjco/hyac180
PMID 36478251
PermalinkURL https://academic.oup.com/jjco/advance-article-pdf/doi/10.1093/jjco/hyac180/47617292/hyac180.pdf