タキザワ マキコ   TAKIZAWA Makiko
  滝沢 牧子
   所属   埼玉医科大学  医学部 総合医療センター 医療安全管理学
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 A Rare Case of Chronic Active Epstein-Barr Virus (EBV) Infection Accompanied by the Infiltration of EBV-infected CD8+ T Cells into the Muscle.
掲載誌名 正式名:Journal of pediatric hematology/oncology
掲載区分国外
巻・号・頁 40(3),e171-e175頁
著者・共著者 Nobuhiko Kobayashi,Takeki Mitsui,Yoshiyuki Ogawa,Hirono Iriuchishima,Makiko Takizawa,Akihiko Yokohama,Takayuki Saitoh,Hiromi Koiso,Norifumi Tsukamoto,Hirokazu Murakami,Yoshihisa Nojima,Hiroshi Handa
発行年月 2018/04
概要 We describe a rare case of chronic active Epstein-Barr virus (CAEBV) infection, with infiltration of the skeletal muscle. A 19-year-old woman with swollen cervical lymph nodes and a fever was referred to our hospital. Swelling of the trapezium muscle and elevation of creatinine kinase level were observed. Biopsy results of the brachialis muscle revealed infiltration of Epstein-Barr virus (EBV)-encoded RNA-positive CD8 T lymphocytes. The EBV virus load in the peripheral blood was high, and EBV monoclonality was determined by Southern blot analysis. Owing to the rarity of CAEBV with skeletal muscle infiltration, this case alerts physicians to the potential diagnostic pitfalls of CAEBV.
DOI 10.1097/MPH.0000000000001026
PMID 29200172