タキザワ マキコ   TAKIZAWA Makiko
  滝沢 牧子
   所属   埼玉医科大学  医学部 総合医療センター 医療安全管理学
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 IgG4-related Disease with a Cardiac Mass.
掲載誌名 正式名:Internal medicine (Tokyo, Japan)
掲載区分国内
巻・号・頁 59(9),1203-1209頁
著者・共著者 Ikuko Matsumura,Takeki Mitsui,Kenichi Tahara,Hiroaki Shimizu,Kunio Yanagisawa,Takuma Ishizaki,Hiromi Koiso,Makiko Takizawa,Akihiko Yokohama,Takayuki Saitoh,Junko Hirato,Hirokazu Murakami,Hiroshi Handa,Norifumi Tsukamoto
発行年月 2020/05/01
概要 A 69-year-old man with palpitations and decreased blood pressure was referred. Echocardiography showed a mass in the right atrium and cardiac septum. The serum IgG4 level was 1,450 mg/dL. A biopsy of the cardiac mass showed fibrosis with inflammatory cells and increased IgG4-positive plasma cells and lymphocytes. Flow cytometry and polymerase chain reaction of the immunoglobulin heavy chain did not demonstrate monoclonality. He was diagnosed with IgG4-related disease (IgG4-RD). IgG4-RD with a cardiac mass is rare and it is difficult to distinguish it from malignant lymphoma by a pathological examination alone. We therefore performed a biopsy and analyzed the clonality in order to make an accurate diagnosis of IgG4-RD.
DOI 10.2169/internalmedicine.4054-19
PMID 31956206