オオヤマ ゲンコウ
OYAMA Genko
大山 彦光 所属 埼玉医科大学 医学部 脳神経内科 職種 教授 |
|
論文種別 | 学術雑誌(原著) |
言語種別 | 日本語 |
査読の有無 | 査読あり |
表題 | Update on deep brain stimulation for movement disorders |
掲載誌名 | 正式名:Clinical Neurology ISSNコード:0009-918X |
巻・号・頁 | 53(11),911-914頁 |
著者・共著者 | Atsushi Umemura,Genko Oyama,Yasushi Shimo,Nobutaka Hattori |
発行年月 | 2013 |
概要 | Deep brain stimulation (DBS) has been widely performed for various medically refractory movement disorders. For Parkinson disease (PD), target of DBS is subthalamic nucleus (STN) or globus pallidus internus (GPi). There are some evidences to demonstrate its effectiveness on motor function and QOL. DBS effectively improves levodopa-responsive motor symptoms, and significantly reduces dyskinesia and motor fluctuations. STN DBS particularly decreases the need for dopaminergic medication. A combination of medical treatment and DBS would provide longer relief of motor symptoms than medical treatment only. Currently new evidence supporting early introduction of DBS for better future outcome is published. DBS of Vim thalamus has been indicated for intractable tremor with various etiologies. Recently posterior subthalamic area (PSA) is introduced as an alternative target to Vim for tremor. GPi DBS is also effective treatment option for generalized dystonia. |
DOI | 10.5692/clinicalneurol.53.911 |
PMID | 24291831 |