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オオヤマ ゲンコウ
OYAMA Genko
大山 彦光 所属 埼玉医科大学 医学部 脳神経内科 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Management of impulse control disorders with deep brain stimulation: A double-edged sword. |
| 掲載誌名 | 正式名：Journal of the neurological sciences |
| 掲載区分 | 国外 |
| 巻・号・頁 | 374,63-68頁 |
| 著者・共著者 | Chayut Kasemsuk,Genko Oyama,Nobutaka Hattori |
| 発行年月 | 2017/03/15 |
| 概要 | Deep brain stimulation (DBS) is a surgical option for advanced Parkinson's disease. Although DBS is used to treat motor fluctuation, DBS may affect non-motor symptoms including mood disorders, cognitive dysfunction, and behavior problems. Impulse control disorders (ICDs) are abnormal behaviors with various manifestations such as pathological gambling, hypersexuality, compulsive shopping, and binge eating, which can affect the quality of life in patients with Parkinson's disease. The effect of DBS on ICD is controversial. Reducing medication by DBS may improve ICDs, however, worsening or even developing new ICDs after DBS can occur. We will review the impact of DBS on ICDs and reveal factors associated with a good response to DBS as well as risk factors for developing ICDs after DBS. We also propose a strategy to manage preexisting ICD and prevent postoperative de novo ICDs. |
| DOI | 10.1016/j.jns.2017.01.019 |
| PMID | 28126343 |