オオヤマ ゲンコウ   OYAMA Genko
  大山 彦光
   所属   埼玉医科大学  医学部 脳神経内科
   職種   教授
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 "Two odd targets" strategy in deep brain stimulation for Parkinson's disease with unilateral levodopa-induced dystonia
掲載誌名 正式名:NEUROLOGY AND CLINICAL NEUROSCIENCE
ISSNコード:2049-4173
出版社 WILEY
巻・号・頁 5(4),129-130頁
著者・共著者 Satoko Sekimoto,Genko Oyama,Takayuki Jo,Asuka Nakajima,Yasushi Shimo,Madoka Nakajima,Atsushi Umemura,Masanobu Ito,Hajime Arai,Nobutaka Hattori
発行年月 2017/07
概要 A 49-year-old man with Parkinson's disease developed wearing-off and levodopa-induced dyskinesia with a dystonic component in the left upper limb. He decided to undergo deep brain stimulation. Asymmetric targets were chosen; for the right side, globus pallidus interna was selected to improve the dystonia in his left upper extremity, and for the left side, the subthalamic nucleus, which had the expected benefit of reducing the patient's medications, was selected. After the surgery, the levodopa-induced dystonia in his left arm was markedly improved, and the levodopa equivalent dose was reduced by 21.4%. The present case suggests that deep brain stimulation with a different target in the left and right hemisphere could be an effective therapeutic option for patients with asymmetric symptoms.
DOI 10.1111/ncn3.12131