スダ　サトシ   SUDA Satoshi   須田　智    所属   埼玉医科大学  医学部 国際医療センター　神経内科・脳卒中内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Efficiency of the Penumbra 5MAX ACE Reperfusion Catheter in Acute Ischemic Stroke Patients
掲載誌名	正式名：JOURNAL OF STROKE & CEREBROVASCULAR DISEASES ISSNコード：1052-3057/1532-8511
出版社	ELSEVIER SCIENCE BV
巻・号・頁	25(12),2981-2986頁
著者・共著者	Kentaro Suzuki,Junya Aoki,Yuki Sakamoto,Takuya Kanamaru,Arata Abe,Satoshi Suda,Seiji Okubo,Kazumi Kimura
発行年月	2016/12
概要	Objective: This study was performed to investigate whether the Penumbra 5MAX ACE is superior to other Penumbra systems. Materials and Methods: We performed a retrospective, single center analysis of patients with acute ischemic stroke with occlusion of the internal carotid artery or middle cerebral artery (M1 segment) who underwent endovascular therapy using a Penumbra system. The reperfusion success rate, puncture-to-revascularization time, and number of passes were assessed. Multivariate regression analysis was conducted to evaluate independent factors related to revascularization within 60 minutes. Successful revascularization was defined by a thrombolysis in cerebral infarction score >= 2b. Results: The Penumbra 5MAX ACE was used in 24 of the 40 patients (60%). Although the revascularization success rate was similar between patient groups (P = .229), the number of passes was significantly lower (1.5 +/- .8 versus 2.6 +/- 1.3, P = .006) and the puncture-to-revascularization time was shorter (50 +/- 26 minutes versus 116 +/- 69 minutes, P = .002) in patients treated with the Penumbra 5MAX ACE. The Penumbra 5MAX ACE was identified as an independent factor for early revascularization (odds ratio, 5.80; P = .041). Among patients with a premorbid modified Rankin Scale score of 0-1, a modified Rankin Scale score of 0-2 at 3 months was observed in 15 of the 19 patients (79%) treated with the Penumbra 5MAX ACE and in 8 of the 16 (50%) who were not (P = .072). Conclusion: Acute revascularization therapy using the Penumbra 5MAX ACE can achieve rapid successful recanalization and tend to improve clinical outcomes.
DOI	10.1016/j.jstrokecerebrovasdis.2016.08.016
PMID	27717681