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スダ サトシ
SUDA Satoshi
須田 智 所属 埼玉医科大学 医学部 国際医療センター 神経内科・脳卒中内科 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Dental-Pulp Stem Cells as a Therapeutic Strategy for Ischemic Stroke |
| 掲載誌名 | 正式名：Biomedicines ISSNコード：/2227-9059 |
| 掲載区分 | 国外 |
| 出版社 | MDPI AG |
| 巻・号・頁 | 10(4),737-737頁 |
| 著者・共著者 | Chikako Nito,Satoshi Suda,Yuko Nitahara-Kasahara,Takashi Okada,Kazumi Kimura |
| 発行年月 | 2022/03/22 |
| 概要 | Regenerative medicine aims to restore human functions by regenerating organs and tissues using stem cells or living tissues for the treatment of organ and tissue defects or dysfunction. Clinical trials investigating the treatment of cerebral infarction using mesenchymal stem cells, a type of somatic stem cell therapy, are underway. The development and production of regenerative medicines using somatic stem cells is expected to contribute to the treatment of cerebral infarction, a central nervous system disease for which there is no effective treatment. Numerous experimental studies have shown that cellular therapy, including the use of human dental pulp stem cells, is an attractive strategy for patients with ischemic brain injury. This review describes the basic research, therapeutic mechanism, clinical trials, and future prospects for dental pulp stem cell therapy, which is being investigated in Japan in first-in-human clinical trials for the treatment of patients with acute cerebral ischemia. |
| DOI | 10.3390/biomedicines10040737 |
| PMID | 35453487 |
| PermalinkURL | https://www.mdpi.com/2227-9059/10/4/737/pdf |