イマイ カズオ   IMAI Kazuo
  今井 一男
   所属   埼玉医科大学  医学部 臨床検査医学(中央検査部)
   職種   専任講師
論文種別 学術雑誌(原著)
言語種別 英語
査読の有無 査読あり
表題 PURE-LAMP Procedure for the Diagnosis of Extrapulmonary Tuberculosis: A Case Series
掲載誌名 正式名:INTERNAL MEDICINE
ISSNコード:09182918
出版社 JAPAN SOC INTERNAL MEDICINE
巻・号・頁 54(11),1447-1450頁
著者・共著者 Yuji Kouzaki,Kei Mikita,Takuya Maeda,Masashi Ishihara,Shuichi Kawano,Yuji Fujikura,Kazuo Imai,Soichiro Kanoh,Kazuho Utsunomiya,Masahiro Inoue,Yasushi Miyahira,Akihiko Kawana
発行年月 2015
概要 Although the polymerase chain reaction is effective for the diagnosis of extrapulmonary tuberculosis (EPTB), it is typically unavailable in resource-limited situations. In contrast, the loop-mediated isothermal amplification (LAMP) assay is a relatively cost-effective and accessible method. Additionally, when combined with the procedure for ultra-rapid extraction (PURE) kit, which enables simple DNA extraction, LAMP can detect Mycobacterium tuberculosis in sputum within 1.5 hours using a simple procedure. In this study, we investigated the utility of the PURE-LAMP technique to diagnose three cases of EPTB and showed that it may potentially be a valuable tool for the diagnosis of EPTB.
DOI 10.2169/internalmedicine.54.4615
PMID 26028005