イマイ　カズオ   IMAI Kazuo   今井　一男    所属   埼玉医科大学  医学部 大学病院　臨床検査医学（中央検査部）    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Chikungunya Fever in Japan Imported from the Caribbean Islands
掲載誌名	正式名：JAPANESE JOURNAL OF INFECTIOUS DISEASES ISSNコード：13446304
出版社	NATL INST INFECTIOUS DISEASES
巻・号・頁	69(2),151-153頁
著者・共著者	Kazuo Imai,Eri Nakayama,Takuya Maeda,Kei Mikita,Yukiko Kobayashi,Aoi Mitarai,Yasuko Honma,Satoru Miyake,Koki Kaku,Yasushi Miyahira,Akihiko Kawana
発行年月	2016/03
概要	A 53-year-old Japanese womanwho was working as a volunteer in the Commonwealth of Dominica in the Caribbean islands presented with a high-grade fever and severe incapacitating generalized arthralgia. The Asian genotype of the chikungunya virus was confirmed using reverse transcription-PCR and serology, based on the presence of a specific neutralization titer and immunoglobulin M antibodies. She was diagnosed with post-chikungunya chronic arthritis based on persistence of her poly arthritis for 3 months and the presence of rheumatoid factor, immunoglobulin G-rheumatoid factor, and matrix metalloproteinase-3. Chikungunya virus should be considered as a causative pathogen in travelers returning from Caribbean islands. Clinicians should consider chikungunya fever in the differential diagnosis of patients who complain of chronic arthritis and have a history of travel to an endemic area.
DOI	10.7883/yoken.JJID.2015.063
PMID	26166501