|
イマイ カズオ
IMAI Kazuo
今井 一男 所属 埼玉医科大学 医学部 臨床検査医学（中央検査部） 職種 専任講師 |
|
| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Assessment of Delayed Large Local Reactions After the First Dose of the SARS-CoV-2 mRNA-1273 Vaccine in Japan. |
| 掲載誌名 | 正式名：JAMA dermatology |
| 巻・号・頁 | 158(8),923-927頁 |
| 著者・共著者 | Toshihide Higashino,Yuki Yamazaki,Satoko Senda,Yushi Satou,Yuiko Yonekura,Kazuo Imai,Junko Arakawa,Shuichi Kawano,Hiroshi Horinosono,Yoshinori Miura |
| 発行年月 | 2022/08 |
| 概要 | Importance: A delayed large local reaction (DLLR) is a delayed-onset adverse skin reaction that may occur after injection of the mRNA-1273 vaccine against SARS-CoV-2. Objective: To examine the associations between sex and age and susceptibility of DLLRs after mRNA-1273 vaccination. Design, Setting, and Participants: This retrospective cross-sectional study was conducted at the Self-Defense Forces large-scale vaccination center in Tokyo, Japan, from May 24 to November 30, 2021. Participants were recipients of the second dose of the mRNA-1273 vaccine who had received the first dose 4 to 6 weeks earlier. Five experienced dermatologists interviewed participants to assess whether they had experienced symptoms of DLLR after administration of the first dose of the vaccine. Exposure: Receipt of the first dose of the mRNA-1273 vaccine. Main Outcomes and Measures: The primary outcome was the incidence rate of DLLR stratified by sex and age group. Odds ratios (ORs) were calculated to evaluate the differences between groups. Outcomes were tested for significance using the Pearson χ2 test with 95% CIs. Results: Of 5893 participants in the study, 3318 (56.3%) were male (median age, 55 years [IQ |
| DOI | 10.1001/jamadermatol.2022.2088 |
| PMID | 35649530 |