カイダ　ケンイチ   KAIDA Kenichi   海田　賢一    所属   埼玉医科大学  医学部 総合医療センター　脳神経内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Guillain-Barré syndrome with IgM antibody to the ganglioside GalNAc-GD1a
掲載誌名	正式名：Journal of Neuroimmunology ISSNコード：01655728
巻・号・頁	113(2),260-267頁
著者・共著者	Ken-ichi Kaida,Susumu Kusunoki,Keiko Kamakura,Kazuo Motoyoshi,Ichiro Kanazawa
発行年月	2001/02
概要	We analyzed the characteristics of 29 Guillain-Barré syndrome (GBS) patients with IgM anti-GalNAc-GD1a antibodies. Fourteen of them had had an antecedent cytomegalovirus infection (CMV group) and12 gastrointestinal infection (G-I group). Most of the G-I group patients (nine of 12) were subsequent to Campylobacter jejuni infection. Electrophysiological results in both groups patients predominantly indicated demyelinating neuropathy. The CMV group patients were characterized by slow progression and frequent facial and sensory deficits. IgM antibodies in their sera recognized an epitope shared by GalNAc-GD1a and GM2. The G-I group patients frequently showed motor type of GBS with cranial nerves spared. IgM antibodies specific to GalNAc-GD1a were present in their sera. © 2001 Elsevier Science B.V.
DOI	10.1016/S0165-5728(00)00451-3
PMID	11164910