カイダ ケンイチ
KAIDA Kenichi
海田 賢一 所属 埼玉医科大学 医学部 総合医療センター 脳神経内科 職種 教授 |
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論文種別 | 学術雑誌(原著) |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Guillain-Barré syndrome associated with IgG monospecific to ganglioside GD1b |
掲載誌名 | 正式名:Neurology ISSNコード:00283878 |
出版社 | Lippincott Williams and Wilkins |
巻・号・頁 | 56(9),1227-1229頁 |
著者・共著者 | T. Miyazaki,Susumu Kusunoki,K. Kaida,M. Shiina,I. Kanazawa |
発行年月 | 2001/05 |
概要 | The authors examined serum antiglycolipid antibodies in 445 patients with Guillain-Barré syndrome (GBS). Among them, nine had anti-GD1b IgG antibodies with no reactivity to other glycolipids tested. All those patients had sensory disturbance, and none had the primary axonal form. Anti-GD1b IgG antibodies may bind to primary sensory neurons and paranodal myelin, where GD1b is localized, and be involved in the pathogenesis of sensory disturbance and demyelination. However, more study is needed to substantiate the roles of anti-GD1b IgG antibodies. |
DOI | 10.1212/WNL.56.9.1227 |
PMID | 11342695 |