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カイダ ケンイチ
KAIDA Kenichi
海田 賢一 所属 埼玉医科大学 医学部 総合医療センター 脳神経内科 職種 教授 |
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| 論文種別 | 学術雑誌(原著) |
| 言語種別 | 日本語 |
| 査読の有無 | 査読あり |
| 表題 | An anti-RNP antibody-positive case of aseptic meningitis induced by non-steroidal anti-inflammatory drugs in a young woman |
| 掲載誌名 | 正式名：Clinical Neurology ISSNコード：0009918X |
| 出版社 | Societas Neurologica Japonica |
| 巻・号・頁 | 58(1),25-29頁 |
| 著者・共著者 | Taro Matsui,Keiichi Nakagawa,Keishi Yamazaki,Taishi Wada,Masato Kadoya,Kenichi Kaida |
| 発行年月 | 2018 |
| 概要 | A 19-year-old woman developed high fever, headache, and nausea after taking Loxoprofen for pharyngitis, followed by disturbed consciousness and nuchal stiffness. The patient and her mother had a history of Raynaud's phenomenon. Cerebrospinal fluid (CSF) examination indicated a diagnosis of aseptic meningitis and revealed high levels of Q albumin and IgG index. Anti-RNP antibodies were positive in serum and CSF. Her symptoms disappeared immediately after cessation of Loxoprofen and a drug lymphocyte stimulation test was negative, confirming a diagnosis of non-steroidal anti-inflammatory drugs (NSAIDs)-induced aseptic meningitis. It should be kept in mind that an immune abnormality such as serum and CSF anti-RNP antibodies may play a role in development of NSAIDs-induced aseptic meningitis. A history of usage of NSAIDs and a thorough examination of collagen diseases are useful for identification of the origin of aseptic meningitis in a young woman. |
| DOI | 10.5692/clinicalneurol.cn-001085 |
| PMID | 29269694 |