イチキ ヨシノブ
ICHIKI Yoshinobu
市来 嘉伸 所属 埼玉医科大学 医学部 国際医療センター 呼吸器外科 職種 専任講師 |
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論文種別 | 学術雑誌(原著) |
言語種別 | 英語 |
査読の有無 | 査読なし |
表題 | Primary pulmonary Ewing's sarcoma: report of a case. |
掲載誌名 | 正式名:Surgery today |
巻・号・頁 | 42(8),812-5頁 |
著者・共著者 | Yoshinobu Ichiki,Akira Nagashima,Yasuhiro Chikaishi,Manabu Yasuda,Ichiro Yamamoto,Satoshi Toyoshima |
発行年月 | 2012/08 |
概要 | The Ewing's sarcoma family of tumors has been reported to originate in a variety of sites, most commonly in the extremities. We herein describe a rare case of primary pulmonary Ewing's sarcoma in a patient with a family history of sarcoma. The patient was a 42-year-old male, who presented with hemoptysis. Chest radiographs revealed a pulmonary mass in the right lower lobe. Clinical and radiological examinations (computed tomography and positron emission tomography) revealed that the lesion was a primary lesion. The lesion was resected by right lower lobectomy. The tumor was located in the pulmonary parenchyma, and there was no evidence of an extrapulmonary involvement by the tumor. Histologically, the tumor was composed of uniform cells with round nuclei and scant cytoplasm which were arranged in cohesive lobules with rare pseudorosette formation. Immunohistochemically, the tumor cells were positive for CD99, and negative for epithelial markers, neuroendocrine markers, myogenic markers and lymphoma markers. This diagnosis was further supported by the cytogenic and reverse transcriptase-polymerase chain reaction findings of EWS/FLI-1 fusion transcripts. This demonstrated the presenc |
DOI | 10.1007/s00595-012-0170-4 |
PMID | 22484982 |