イチキ　ヨシノブ   ICHIKI Yoshinobu   市来　嘉伸    所属   埼玉医科大学  医学部 国際医療センター　呼吸器外科    職種   専任講師
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Difficulty of treatment for pleural epithelioid hemangioendothelioma: a report of a case.
掲載誌名	正式名：General thoracic and cardiovascular surgery
巻・号・頁	68(2),190-193頁
著者・共著者	Masaru Takenaka,Yoshinobu Ichiki,Yusuke Nabe,Yojiro Tsuda,Taiji Kuwata,Yasuhiro Chikaishi,Ayako Hirai,Naoko Imanishi,Kazue Yoneda,Fumihiro Tanaka
発行年月	2020/02
概要	We herein report the case of a 62-year-old man who underwent extrapleural pneumonectomy (EPP) for pleural epithelial hemangioendothelioma (EHE) diagnosed by a pleural biopsy. Pre-operative computed tomography revealed diffuse pleural thickening and pleural effusion in the right thoracic cavity, although metastasis to neither the lymph nodes nor distant organs was detected. We decided to perform EPP based on surgical findings that the tumor had invaded the lung parenchyma. A pathological examination revealed tumor invasion of the lung parenchyma, blood vessel, pericardium, diaphragm and bronchial wall. Despite aggressive treatment, tumor recurrence was detected about 1 month after surgery. Although we controlled the tumor progression using pazopanib, the patient ultimately died 3.5 months after the operation. Pleural EHE is a very rare disease that has a poor prognosis due to its high malignant potential. It is important to formulate strategies matched to individual cases based on disease progression and invasiveness of treatment.
DOI	10.1007/s11748-019-01135-1
PMID	31049818