ジュウジョウ　ケンタロウ   JUJO Kentaro   重城　健太郎    所属   埼玉医科大学  医学部 総合医療センター　心臓内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Intimal disruption affects drug-eluting cobalt-chromium stent expansion: A randomized trial comparing scoring and conventional balloon predilation
掲載誌名	正式名：INTERNATIONAL JOURNAL OF CARDIOLOGY ISSNコード：01675273
出版社	ELSEVIER IRELAND LTD
巻・号・頁	221,23-31頁
著者・共著者	Kentaro Jujo,Katsumi Saito,Issei Ishida,Ahsung Kim,Yuki Suzuki,Yuho Furuki,Taisuke Ouchi,Yasuhiro Ishii,Haruki Sekiguchi,Junichi Yamaguchi,Hiroshi Ogawa,Nobuhisa Hagiwara
発行年月	2016/10
概要	Background: Stent expansion remains one of the most important predictors of restenosis and subacute thrombosis, even with the use of drug-eluting stents. This study was designed to clarify the impact of lesion preparation on final stent expansion.Methods: Sixty-six consecutive patients were included in this trial, and ultimately 52 enrolled non-calcified de novo lesions were randomly assigned to undergo single predilation with either a semi-compliant scoring balloon or a semi-compliant conventional balloon. Lesions were treated with a single 2.5- to 3.0-mm cobalt-chromium everolimus-eluting stent under optical coherence tomography (OCT) guidance without post-stenting dilation. Stent expansion was defined as the ratio of OCT-measured minimum stent area to the predicted stent area.Results: Stent expansion was significantly higher after predilation by a scoring balloon (68.0% vs. 62.1%, p=0.017) with similar stent lumen eccentricity (0.84 vs. 0.80, p=0.18). Intimal disruption was induced significantly more frequently (68.0% vs. 38.4%, p = 0.035) and was more extensive in the scoring group (122 degrees vs. 65 degrees, p = 0.038). Lesions with intimal disruption after predilation achi
DOI	10.1016/j.ijcard.2016.07.002