ジュウジョウ　ケンタロウ   JUJO Kentaro   重城　健太郎    所属   埼玉医科大学  医学部 総合医療センター　心臓内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	AVJ-514 Trial - Baseline Characteristics and 30-Day Outcomes Following MitraClip (R) Treatment in a Japanese Cohort
掲載誌名	正式名：CIRCULATION JOURNAL ISSNコード：13469843
出版社	JAPANESE CIRCULATION SOC
巻・号・頁	81(8),1116-1122頁
著者・共著者	Kentaro Hayashida,Satoshi Yasuda,Takashi Matsumoto,Makoto Amaki,Shingo Mizuno,Tetsuya Tobaru,Kentaro Jujo,Tatsushi Ootomo,Junichi Yamaguchi,Keiichi Fukuda,Shigeru Saito,Elyse Foster,Atif Qasim,Masafumi Kitakaze,Ryohei Yozu,Morimasa Takayama
発行年月	2017/08
概要	Background: The MitraClip (R) system is a transcatheter-based therapeutic option for patients with chronic mitral regurgitation (MR) who are at high risk for surgery. A prospective, multicenter, single-arm study was initiated to confirm the transferability of this system to Japan.Methods and Results: Patients with symptomatic chronic moderate-to-severe (3+) or severe (4+) functional or degenerative MR with a Society of Thoracic Surgery (STS) score>= 8%, or the presence of 1 predefined risk factor were enrolled. Patients with left ventricular (LV) ejection fraction (EF)<30% were excluded. MR severity and LV function were assessed by an independent echo-cardiography core lab. Primary outcome included major adverse events (MAE) at 30 days and acute procedural success (APS). A total of 30 patients (age: 80 +/- 7 years; STS score: 10.3 +/- 6.6%) were treated with the MitraClip (R). At baseline, all patients had MR 3+/4+ with 53%/47% patients with degenerative/functional etiology with mean LVEF of 50.2 +/- 12.8%, and 37% of patients were NYHA class III/IV. APS was achieved in 86.7% with no occurrence of MAE. At 30 days, 86.7% of patients had MR<= 2+ and 96.7% were NYHA class
DOI	10.1253/circj.CJ-17-0115