ジュウジョウ　ケンタロウ   JUJO Kentaro   重城　健太郎    所属   埼玉医科大学  医学部 総合医療センター　心臓内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Clinical characteristics and long-term outcomes of rotational atherectomy: J2T multicenter registry
掲載誌名	正式名：Circulation Journal ISSNコード：13474820
出版社	Japanese Circulation Society
巻・号・頁	82(2),369-375頁
著者・共著者	Iwao Okai,Tomotaka Dohi,Shinya Okazaki,Kentaro Jujo,Makoto Nakashima,Hisao Otsuki,Kazuki Tanaka,Hiroyuki Arashi,Ryuta Okabe,Fukuko Nagura,Yugo Nara,Hiroshi Tamura,Takeshi Kurata,Hideyuki Kawashima,Hiroyuki Kyono,Junichi Yamaguchi,Katsumi Miyauchi,Ken Kozuma,Nobuhisa Hagiwara,Hiroyuki Daida
発行年月	2018
概要	Background: Rotational atherectomy (RA) is an adjunct tool for the management of heavily calcified coronary lesions during percutaneous coronary intervention (PCI), but the long-term clinical outcomes of RA use remain unclear in this drug-eluting stent era. Methods and Results: This multi-center registry assessed the characteristics and outcomes of patients treated by RA for calcified coronary lesions between 2004 and 2015. Among 1,090 registered patients, mean age was 70±10 years and 815 (75%) were male. Sixty percent of patients had diabetes mellitus and 27.7% were receiving hemodialysis. The procedure was successful in 96.2%. In-hospital death occurred in 33 patients (3.0%), and 14 patients (1.3%) developed definite/probable stent thrombosis. During the median follow-up period of 3.8 years, the incidence of major adverse cardiac events (MACE), defined as all-cause death, acute coronary syndrome, stent thrombosis, target vessel revascularization and stroke, was 46.7%. On multivariable Cox hazard analysis, hemodialysis (HR, 2.08 95% CI: 1.53–2.86 P&lt0.0001) and age (HR, 1.03 95% CI: 1.01–1.04 P&lt0.0001) were strong independent predictors of MACE. Conversely, statin tr
DOI	10.1253/circj.CJ-17-0668
PMID	28931790