ジュウジョウ　ケンタロウ   JUJO Kentaro   重城　健太郎    所属   埼玉医科大学  医学部 総合医療センター　心臓内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Sex differences in clinical outcomes after rotational atherectomy of calcified coronary stenoses: from multicenter registry
掲載誌名	正式名：AMERICAN JOURNAL OF CARDIOVASCULAR DISEASE ISSNコード：2160200X
出版社	E-CENTURY PUBLISHING CORP
巻・号・頁	11(1),12-+頁
著者・共著者	Hisao Otsuki,Kentaro Jujo,Kazuki Tanaka,Iwao Okai,Makoto Nakashima,Tomotaka Dohi,Shinya Okazaki,Ryuta Okabe,Fukuko Nagura,Yugo Nara,Hideyuki Kawashima,Hiroyuki Kyono,Hiroyuki Arashi,Junichi Yamaguchi,Hiroshi Tamura,Takeshi Kurata,Katsumi Miyauchi,Ken Kozuma,Hiroyuki Daida,Nobuhisa Hagiwara
発行年月	2021
概要	Background: Recent improvements in devices and medications may diminish the risk of adverse events following percutaneous coronary intervention (PCI) in women. However, complex calcified coronary lesions are increasingly being encountered in clinical practice, which remain challenging for contemporary PCI. Rotational atherectomy (RA) of severely calcified lesions is an option that facilitates the technical success of PCI. We aimed to examine sex differences in long-term clinical prognoses after PCI with RA in the drug-eluting stent (DES) era. Methods and results: We evaluated J2T ROTA registry data from 1,090 patients with severely calcified de novo coronary artery stenoses who underwent PCI using RA at 3 hospitals between 2004 and 2015. After excluding patients who received regular hemodialysis, 788 patients, including 570 men and 218 women, were ultimately analyzed. The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCE), which included death, acute coronary syndrome (ACS), andstroke. The women were significantly older, and presented more frequently with chronic kidney disease, ACS, atrial fibrillation, lower body mass indexes, and worse lipid pr