ジュウジョウ　ケンタロウ   JUJO Kentaro   重城　健太郎    所属   埼玉医科大学  医学部 総合医療センター　心臓内科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Impact of Social Frailty in Hospitalized Elderly Patients With Heart Failure: A FRAGILE-HF Registry Subanalysis.
掲載誌名	正式名：Journal of the American Heart Association
巻・号・頁	10(17),e019954頁
著者・共著者	Kentaro Jujo,Nobuyuki Kagiyama,Kazuya Saito,Kentaro Kamiya,Hiroshi Saito,Yuki Ogasahara,Emi Maekawa,Masaaki Konishi,Takeshi Kitai,Kentaro Iwata,Hiroshi Wada,Takatoshi Kasai,Hirofumi Nagamatsu,Tetsuya Ozawa,Katsuya Izawa,Shuhei Yamamoto,Naoki Aizawa,Ryusuke Yonezawa,Kazuhiro Oka,Hyuma Makizako,Shin-Ichi Momomura,Yuya Matsue
発行年月	2021/09
概要	Background Frailty is conceptualized as an accumulation of deficits in multiple areas and is strongly associated with the prognosis of heart failure (HF). However, the social domain of frailty is less well investigated. We prospectively evaluated the clinical characteristics and prognostic impact of social frailty (SF) in elderly patients with HF. Methods and Results FRAGILE-HF (prevalence and prognostic value of physical andsocial frailty in geriatric patients hospitalized for heart failure) is a multicenter, prospective cohort study focusing on patients hospitalized for HF and aged ≥65 years. We defined SF by Makizako's 5 items, which have been validated as associated with future disability. The primary end point was a composite of all-cause death and rehospitalization because of HF. The impact of SF on all-cause mortality alone was also evaluated. Among 1240 enrolled patients, 825 (66.5%) had SF. During the 1-year observation period after discharge, the rates of the combined end point and all-cause mortality were significantly higher in patients with SF than in those without SF (Log-rank test: both P < 0.05). SF remained as significantly associated with both the combined
DOI	10.1161/JAHA.120.019954
PMID	34472374