セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Antimicrobial susceptibilities of potential bacterial pathogens in adults with acute respiratory tract infections: Prospective Epidemiological Network Investigating Community-acquired Infection SurveiLLance in Nagasaki (PENICILLIN) Study
掲載誌名	正式名：Diagnostic Microbiology andInfectious Disease ISSNコード：07328893
出版社	Elsevier Inc.
巻・号・頁	51(4),271-280頁
著者・共著者	Yoichi Hirakata,Katsunori Yanagihara,Yoshitsugu Miyazaki,Kazunori Tomono,Intetsu Kobayashi,Shigeru Kohno,Hiroshi Kakeya,Masafumi Hayashida,Ken Shinzato,Minoru Yokota,Yukiharu Yoshio,Kohta Kohno,Yukinobu Mishima,Tetsuhide Hoshiko,Kiyomi Hoshiko,Yasunori Onitsuka,Nobuaki Iwanaga,Kohji Hashiguchi,Masaaki Fukuda,Misuzu Kuroki,Masafumi Seki,Osamu Era,Ryozo Ogushi,Fumihiro Akashi,Noboru Yoshida,Masahiro Kuwatsuka,Hidemi Ide,Kenichiro Inoue,Toyohiro Sasaki,Reijiro Migita,Kiyoto Hirose,Kazuhiko Takuma,Kazuhiko Takashima,Keiko Iida,Masao Nakatomi,Hironori Tanaka,Kazunori Shimoguchi,Akira Sakamoto,Yukio Imamura,Satoshi Funakoshi,Katsunori Kurobe,Hideki Tagawa,Naofumi Suyama,Kazuyuki Imamura,Chizu Fukushima,Yasumasa Dohtu,Kaoru Kawakami,Teturo Kanda,Kazuo Sasayama,Hiroshi Takaya,Hiroko Tsurutani,Ryoji Yoshida,Tateo Imanishi,Shigeru Kawabata,Kyusuke Nakamura
発行年月	2005
概要	The prevalence and the antimicrobial susceptibilities of bacterial pathogens in acute upper respiratory tract infections (AURTIs) is not clear. We conducted a prospective community-based multicenter study in 45 centers across Nagasaki, Japan, between December 2001 and April 2002. We examined the nasopharyngeal or throat isolates in 930 adult outpatients with AURTIs. Potential bacterial pathogens, including Streptococcus pyogenes (from 6.8% patients), S. pneumoniae (5.3%), S. milleri group (2.0%), Staphylococcus aureus (26.0%), Moraxella catarrhalis (7.4%), Haemophilus influenzae (17.6%), and Klebsiella pneumoniae (1.2%), were isolated from 51.8% of the patients. Penicillin nonsusceptible phenotype accounted for 44.9% of S. pneumoniae isolates. Among Staphylococcus aureus isolates, 9.1% were methicillin-resistant. In H. influenzae isolates, 6.7% produced β-lactamase and 23.2% were β-lactamase-negative ampicillin-resistant. The results indicated that the potential bacterial pathogens were detected in the remarkable population of the adults with AURTIs and the current antimicrobial susceptibilities of such pathogens. © 2005 Elsevier Inc. All rights reserved.
DOI	10.1016/j.diagmicrobio.2004.11.008