セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読なし
表題	Severe Legionnaires' disease successfully treated using a combination of fluoroquinolone, erythromycin, corticosteroid, and sivelestat.
掲載誌名	正式名：Internal medicine (Tokyo, Japan) ISSNコード：09182918
巻・号・頁	47(8),773-7頁
著者・共著者	Hiroshi Kakeya,Naomi Ehara,Kiyoyasu Fukushima,Masafumi Seki,Koichi Izumikawa,Yoshihiro Yamamoto,Katsunori Yanagihara,Atsushi Saito,Shigeru Kohno
発行年月	2008
概要	The patient was a 67-year-old man with diabetes mellitus who had been to a hot spring spa a few days before his admission. The diagnosis of Legionella pneumonia was made using a urinary antigen assay. Intravenous pazufloxacin and oral clarithromycin were started. However, despite these treatments, he developed acute respiratory distress syndrome (ARDS). He was administered the combination of intravenous pazufloxacin and erythromycin, corticosteroid, and sivelestat for two weeks. Then he was successfully recovered. The outcome suggests that treatment with corticosteroid and sivelestat, in addition to a combination of appropriate anti-Legionella antibiotics, should be considered for patients with severe Legionella pneumonia with ARDS.
DOI	10.2169/internalmedicine.47.0677
NAID	130000080040
PMID	18421197