セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Methicillin-resistant Staphylococcus aureus bacteremia at a university hospital in Japan.
掲載誌名	正式名：Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy ISSNコード：14377780
出版社	Japanese Society for Cancer Chemotherapy
巻・号・頁	18(6),841-7頁
著者・共著者	Masaaki Isobe,Etsuko Uejima,Masafumi Seki,Yoshiaki Yamagishi,Koji Miyawaki,Kaori Yabuno,Mari Masaoka,Shigeto Hamaguchi,Nori Yoshioka,Kazunori Tomono
発行年月	2012/12
概要	Methicillin-resistant Staphylococcus aureus (MRSA) has become a leading cause of infections in hospitals, and mortality from MRSA bacteremia is high. In this study, we assessed the clinical characteristics and optimum management of 115 patients with MRSA bacteremia who were admitted to Osaka University Hospital between January 2006 and December 2010. Sixty-nine of the patients survived and 46 died of heart failure or renal failure. The nonsurvivors had reduced levels of platelets and albumin, and increased aspartate aminotransferase, total bilirubin, blood urea nitrogen, and creatinine levels. Other causes of death included sepsis, septic shock plus respiratory failure, disseminated intravascular coagulation, and unknown causes. However, a significant number of those whose infections were catheter-derived survived. Nonsurvivors were more often administered catecholamines and consultation with an infection-control team (ICT) was significantly associated with improved survival. Patients about whom the ICT were consulted were administered significantly more additional anti-MRSA drugs, for example trimethoprim-sulfamethoxazole, clindamycin, and gentamycin, than patients who were not th
DOI	10.1007/s10156-012-0423-6
PMID	22576750