セキ　マサフミ   SEK Masafumi   関　雅文    所属   埼玉医科大学  医学部 国際医療センター　感染症科・感染制御科    職種   教授
論文種別	学術雑誌(原著)
言語種別	英語
査読の有無	査読あり
表題	Polymerase chain reaction-based active surveillance of MRSA in emergency department patients.
掲載誌名	正式名：Infection and drug resistance ISSNコード：11786973
出版社	Dove Medical Press Ltd.
巻・号・頁	8,113-8頁
著者・共著者	Masafumi Seki,Hiroki Takahashi,Norihisa Yamamoto,Shigeto Hamaguchi,Masahiro Ojima,Tomoya Hirose,Kazuhisa Yoshiya,Hiroshi Ogura,Takeshi Shimazu,Kazunori Tomono
発行年月	2015
概要	Conventional culture methods to detect methicillin-resistant Staphylococcus aureus (MRSA) take a few days, and their sensitivity and usefulness also need to be improved. In this study, active screening was performed using the polymerase chain reaction (PCR) for colonization with MRSA on admission and follow-up surveillance after admission to an emergency department between June 2012 and August 2012, and the backgrounds of PCR and/or culture-method-positive patients were compared. Among 95 patients, 15 (15.8%) patients were positive for MRSA on PCR and/or culture; 6.3% (6/95) of patients were positive on admission, and 9.5% (9/95) became positive during the stay after admission. The major primary diagnoses in MRSA-positive patients were trauma and cerebrovascular diseases. Nine (60%) of 15 patients were MRSA-positive on both PCR and culture, compared with three (20%) of 15 who were PCR-positive but culture-negative. The other three (20%) of 15 patients were PCR-negative but culture-positive. Furthermore, there was a tendency for younger age and shorter stay to be associated with PCR-positive but culture-negative results. These findings suggest that active surveillance with PCR may b
DOI	10.2147/IDR.S80123
PMID	25999747